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1

Clinical Development and Commercialization of Advanced Therapy Medicinal Products (ATMPs) in the EU: how are the product pipeline and regulatory framework evolving?

Boráň, Tomáš, Menezes-Ferreira, Margarida, Reischl, Ilona, Celis, Patrick, Ferry, Nicolas, Gänsbacher, Bernd, Krafft, Hartmut, Lipucci Di Paola, Michele, Sladowski, Dariusz, Salmikangas, Paula

Journal:

Human Gene Therapy Clinical Development

Year:

2017

Language:

english

File:

PDF, 1.25 MB

english, 2017

2

SCHWANN CELL SEEDED GUIDANCE TUBES RESTORE ERECTILE FUNCTION AFTER ABLATION OF CAVERNOUS NERVES IN RATS

MAY, F., WEIDNER, N., MATIASEK, K., CASPERS, C., MRVA, T., VROEMEN, M., HENKE, J., LEHMER, A., SCHWAIBOLD, H., ERHARDT, W., GÄNSBACHER, B., HARTUNG, R.

Journal:

The Journal of Urology

Year:

2004

Language:

english

File:

PDF, 457 KB

english, 2004

3

Tissue Engineering of the Anterior Cruciate Ligament—Sodium Dodecyl Sulfate-Acellularized and Revitalized Tendons Are Inferior to Native Tendons

Tischer, Thomas, Aryee, Sebastian, Wexel, Gabriele, Steinhauser, Erwin, Adamczyk, Christopher, Eichhorn, Stefan, Milz, Stefan, Martinek, Vladimir, Gänsbacher, Bernd, Imhoff, Andreas B., Vogt, Stephan

Journal:

Tissue Engineering Part A

Year:

2010

Language:

english

File:

PDF, 22.75 MB

english, 2010

4

Physicobiochemical Synergism Through Gene Therapy and Functional Tissue Engineering for In Vitro Chondrogenesis

Salzmann, Gian M., Nuernberger, Benedikt, Schmitz, Philipp, Anton, Martina, Stoddart, Martin J., Grad, Sibylle, Milz, Stefan, Tischer, Thomas, Vogt, Stephan, Gansbacher, Bernd, Imhoff, Andreas B., Ali

Journal:

Tissue Engineering Part A

Year:

2009

Language:

english

File:

PDF, 62.72 MB

english, 2009

5

Magnetofection: enhancing and targeting gene delivery by magnetic force in vitro and in vivo

Scherer, F, Anton, M, Schillinger, U, Henke, J, Bergemann, C, Krüger, A, Gänsbacher, B, Plank, C

Journal:

Year:

2002

Language:

english

File:

PDF, 1.17 MB

english, 2002

6

Recent developments in gene therapy for oncology and hematology

M.A Roskrow, B Gänsbacher

Journal:

Critical Reviews in Oncology/Hematology

Year:

1998

Language:

english

File:

PDF, 115 KB

english, 1998

7

Plasminogen Activator Inhibitor-2, but Not Cystatin C, Inhibits the Prometastatic Activity of Tissue Inhibitor of Metalloproteinases-1 in the Liver

Kopitz, Charlotte, Gerg, Michael, Gansbacher, Bernd, Krüger, Achim

Journal:

Human Gene Therapy

Year:

2008

Language:

english

File:

PDF, 574 KB

english, 2008

8

Characterization of the Recombinant Adenovirus Vector AdYB-1: Implications for Oncolytic Vector Development

Glockzin, G., Mantwill, K., Jurchott, K., Bernshausen, A., Ladhoff, A., Royer, H.-D., Gansbacher, B., Holm, P. S.

Journal:

Journal of Virology

Year:

2006

Language:

english

File:

PDF, 415 KB

english, 2006

9

Optimization of radiation controlled gene expression by adenoviral vectors in vitro

Anton, Martina, Gomaa, Iman E O, von Lukowicz, Tobias, Molls, Michael, Gansbacher, Bernd, Würschmidt, Florian

Journal:

Cancer Gene Therapy

Year:

2005

Language:

english

File:

PDF, 182 KB

english, 2005

10

Effects of cold atmospheric plasmas on adenoviruses in solution

Zimmermann, J L, Dumler, K, Shimizu, T, Morfill, G E, Wolf, A, Boxhammer, V, Schlegel, J, Gansbacher, B, Anton, M

Journal:

Journal of Physics D Applied Physics

Year:

2011

Language:

english

File:

PDF, 751 KB

english, 2011

11

Regulation of HLA-DR, DP, and DQ expression in activated T cells

Bernd Gansbacher, Karen S. Zier

Journal:

Cellular Immunology

Year:

1988

Language:

english

File:

PDF, 1.72 MB

english, 1988

12

STRUCTURAL AND MOLECULAR ANALYSIS OF ERECTILE NERVE REPAIR

Florian May, Dieter Saur, Maurice Vroemen, Kaspar Matiasek, Max Apprich, Christian Arndt, Antonie Lehmer, Armin Blesch, Norbert Weidner, Bernd Gansbacher, Rudolf Hartung

Journal:

European Urology Supplements

Year:

2006

Language:

english

File:

PDF, 47 KB

english, 2006

13

LB9 Glial cell line-derived neurotrophic factor-hypersecreting schwann cell grafts restore erectile function after ablation of cavernous nerve segments

F. May, N. Weidner, K. Matiasek, C. Caspers, T. Mrva, M. Vroemen, J. Henke, A. Lehmer, A. Blesch, W. Erhardt, B. Gänsbacher, R. Hartung

Journal:

European Urology Supplements

Year:

2004

Language:

english

File:

PDF, 187 KB

english, 2004

14

IL2 treatment for cancer: from biology to gene therapy

Foa, R, Guarini, A, Gansbacher, B

Journal:

British Journal of Cancer

Year:

1992

Language:

english

File:

PDF, 1.66 MB

english, 1992

15

Retroviral gene transfer induced constitutive expression of interleukin- 2 or interferon-gamma in irradiated human melanoma cells

Gansbacher, B, Zier, K, Cronin, K, Hantzopoulos, PA, Bouchard, B, Houghton, A, Gilboa, E, Golde, D

Journal:

Year:

1992

File:

PDF, 2.49 MB

1992

16

[IEEE 2012 IEEE 39th International Conference on Plasma Sciences (ICOPS) - Edinburgh (2012.07.8-2012.07.13)] 2012 Abstracts IEEE International Conference on Plasma Science - Effects of cold atmospheric plasmas on adenoviruses in solution

Zimmermann, Julia L., Shimizu, Tetsuji, Morfill, Gregor E., Boxhammer, Veronika, Schlegel, Jurgen, Dumler, Katja, Wolf, Anja, Gansbacher, Bernd, Anton, Martina

Year:

2012

Language:

english

File:

PDF, 95 KB

english, 2012

17

Transduction of the IL2 Gene Into Human Acute Leukemia Cells: Induction of Tumor Rejection Without Modifying Cell Proliferation and IL2 Receptor Expression

Cignetti, A., Guarini, A., Carbone, A., Forni, M., Cronin, K., Forni, G., Gansbacher, B., Foa, R.

Journal:

JNCI Journal of the National Cancer Institute

Year:

1994

Language:

english

File:

PDF, 3.68 MB

english, 1994

18

Angiogenesis Gene Therapy - A New Innovation Push in Plastic Surgery?

Giunta, R. E., Gänsbacher, B.

Journal:

Handchirurgie · Mikrochirurgie · Plastische Chirurgie

Year:

2005

Language:

german

File:

PDF, 45 KB

german, 2005

19

European school of Oncology position paper. Gene therapy for the medical oncologist

M. Blaese, T. Blankenstein, M. Brenner, O. Cohen-Haguenauer, B. Gansbacher, B. Sorrentino, T. Velu

Journal:

European Journal of Cancer

Year:

1995

Language:

english

File:

PDF, 1.02 MB

english, 1995

20

199Effects of a new oncolytic adenovirus (XVIR) in human prostate cancer cell lines and in xenograph mouse model

U. Treiber, K. Mantwill, N. Köhler Vargas, A. Bernshausen, R. Paul, H. Van Randenborgh, H. Kübler, N. Zantl, R. Hartung, B. Gänsbacher, P.S. Holm

Journal:

European Urology Supplements

Year:

2005

Language:

english

File:

PDF, 198 KB

english, 2005

21

310 Mitogen induced helper and suppressor activity mediated by OKT 4+ cells

GANSBACHER, B, LEVINSON, A

Journal:

Journal of Allergy and Clinical Immunology

Year:

1985

Language:

english

File:

PDF, 141 KB

english, 1985

22

Good News on the Clinical Gene Transfer Front

Wilson, James M., Gansbacher, Bernd, Berns, Kenneth I., Bosch, Fatima, Kay, Mark A., Naldini, Luigi, Wei, Yu-Quan

Journal:

Human Gene Therapy

Year:

2008

Language:

english

File:

PDF, 41 KB

english, 2008

23

Gentherapeutische Möglichkeiten in der Knorpeltherapie

S. Vogt, P. Ueblacker, V. Martinek, B. Gänsbacher, A. B. Imhoff

Journal:

Year:

2005

Language:

german

File:

PDF, 760 KB

german, 2005

24

[IEEE 4th IEEE Conference on Nanotechnology, 2004. - Munich, Germany (16-19 Aug. 2004)] 4th IEEE Conference on Nanotechnology, 2004. - Localized nucleic acid delivery to living cells using nanobiotechnology approaches

Plank, C., Schillinger, U., Hacker, C., Brill, T., Rudolph, C., Krotz, F., Hirschberger, J., Stemberger, A., Gansbacher, B.

Year:

2004

Language:

english

File:

PDF, 240 KB

english, 2004

25

Human tumor vaccines and genetic engineering of tumors with cytokine and histocompatibility genes to enhance immunogenicity

Rosenthal, Felicia M., Zier, Karen S., Gansbacher, Bernd

Journal:

Current Opinion in Oncology

Year:

1994

File:

PDF, 479 KB

1994

26

Prediction of flap necrosis with laser induced indocyanine green fluorescence in a rat model

R.E. Giunta, T. Holzbach, C. Taskov, P.S. Holm, T. Brill, R. Busch, B. Gansbacher, E. Biemer

Journal:

British Journal of Plastic Surgery

Year:

2005

Language:

english

File:

PDF, 644 KB

english, 2005

27

Schwann cell grafts are superior to autologous nerve grafts for repair of ablated cavernosal nerves in rats

F. May, N. Weidner, T. Mrya, C. Caspers, B. Gänsbacher, R. Hartung

Journal:

European Urology Supplements

Year:

2003

Language:

english

File:

PDF, 199 KB

english, 2003

28

Retroviral Vector—Mediated Cytokine-Gene Transfer into Tumor Cells

Gansbacher, Bernd, Rosenthal, Felicia M., Zier, Karen

Journal:

Cancer Investigation

Year:

1993

Language:

english

File:

PDF, 964 KB

english, 1993

29

Report of a second serious adverse event in a clinical trial of gene therapy for X-linked severe combined immune deficiency (X-SCID) : Position of the European Society of Gene Therapy (ESGT)

Bernd Gansbacher

Journal:

The Journal of Gene Medicine

Year:

2003

Language:

english

File:

PDF, 41 KB

english, 2003

30

Quantification of transgene expression using herpes virus thymidine kinase and radioiodinated fiau

R. Haubner, M. Anton, S. Gertz, A. Krüger, B. Gansbacher, M. Schwaiger, N. Avril

Journal:

Journal of Labelled Compounds and Radiopharmaceuticals

Year:

2001

Language:

english

File:

PDF, 247 KB

english, 2001

31

532. Effects of a New YB-1 Dependent Adenovirus (XVir) in Human Prostate Cancer Cell Lines and in a Xenograft Mouse Model

MANTWILL, K, KOEHLERVARGAS, N, BERNSHAUSEN, A, TREIBER, U, HARTUNG, R, GANSBACHER, B, HOLM, P

Journal:

Molecular Therapy

Year:

2005

Language:

english

File:

PDF, 79 KB

english, 2005

32

Use of the norepinephrine transporter as a reporter gene for non-invasive imaging of genetically modified cells

Martina Anton, Bettina Wagner, Roland Haubner, Claudia Bodenstein, Bryan E. Essien, Heinz Bönisch, Markus Schwaiger, Bernd Gansbacher, Wolfgang A. Weber

Journal:

The Journal of Gene Medicine

Year:

2004

Language:

english

File:

PDF, 251 KB

english, 2004

33

Human lung tumor cell secretion of interleukin-2 for protection against tumor engraftment

Thomas Alosco, Bernd Gansbacher, Richard Bankert, Hiroshi Takita, Nicholas Petrelli

Journal:

Annals of Surgical Oncology

Year:

1994

Language:

english

File:

PDF, 864 KB

english, 1994

34

14.2 Monitoring of cardiac transgene expression in vivo using radiolabeled FIAU in combination with the herpesviral thymidinekinase marker gene (HSVl-tk)

BENGEL, F, ANTON, M, BRILL, T, HAUBNER, R, NGUYEN, N, GANSBACHER, B, AVRIL, N, SCHWAIGER, M

Journal:

Journal of Nuclear Cardiology

Year:

2001

Language:

english

File:

PDF, 153 KB

english, 2001

35

Cancer Gene Therapy: Present and Future

Bonini, Chiara, Gansbacher, Bernd

Journal:

Human Gene Therapy

Year:

2009

Language:

english

File:

PDF, 30 KB

english, 2009

36

Combined Reporter Gene PET and Iron Oxide MRI for Monitoring Survival and Localization of Transplanted Cells in the Rat Heart

Higuchi, T., Anton, M., Dumler, K., Seidl, S., Pelisek, J., Saraste, A., Welling, A., Hofmann, F., Oostendorp, R. A.J., Gansbacher, B., Nekolla, S. G., Bengel, F. M., Botnar, R. M., Schwaiger, M.

Journal:

Journal of Nuclear Medicine

Year:

2009

Language:

english

File:

PDF, 1.46 MB

english, 2009

37

AdVEGF165 gene transfer increases survival in overdimensioned skin flaps

R. E. Giunta, T. Holzbach, C. Taskov, P. S. Holm, M. A. Konerding, D. Schams, E. Biemer, B. Gänsbacher

Journal:

The Journal of Gene Medicine

Year:

2005

Language:

english

File:

PDF, 311 KB

english, 2005

38

Letter to the editors of Nature from the American Society of Gene Therapy (ASGT) and the European Society of Gene Therapy (ESGT)

Donald B Kohn, Bernd Gänsbacher

Journal:

The Journal of Gene Medicine

Year:

2003

Language:

english

File:

PDF, 26 KB

english, 2003

39

Heterogeneity ofHLAdefined in PLT: A cellular assay detects differences not seen using HLA-DRw serology

Karen S. Zier, Bernd Gänsbacher, Sigfried Scholz, Ekkehard D. Albert

Journal:

Year:

1980

Language:

english

File:

PDF, 480 KB

english, 1980

40

In vivo imaging of herpes simplex virus type 1 thymidine kinase gene expression: early kinetics of radiolabelled FIAU

Roland Haubner, Norbert Avril, Petros A. Hantzopoulos, Bernd Gansbacher, Markus Schwaiger

Journal:

European Journal of Nuclear Medicine and Molecular Imaging

Year:

2000

Language:

english

File:

PDF, 152 KB

english, 2000

41

A Pilot Study of Immunization with Interleukin-2 Secreting Allogeneic HLA-A2 Matched Renal Cell Carcinoma Cells in Patients with Advanced Renal Cell Carcinoma

Gansbacher, Bernd, Motzer, Robert, Houghton, Alan, Bander, Neil, Minasian, Lori, Gastl, Guenther, Rosenthal, Felicia, Gilboa, Eli, Scheinfeld, Joel, Yang, Soo Young, Wong, George, Golde, David, Reuter

Journal:

Human Gene Therapy

Year:

1992

File:

PDF, 2.43 MB

1992

42

1070. Easy Search on Clinical Gene Transfer: The Euregenethy (EC-DG Research FP5-TN) Data Base on Pre-Clinical & Clinical Gene Transfer & Therapy

COHENHAGUENAUER, O, BOSCH, F, CARRONDO, M, CICHUTEK, K, DEGLON, N, DEMENEIX, B, DICKSON, G, GARHTON, G, GANSBACHER, B, MELANI, C

Journal:

Molecular Therapy

Year:

2005

Language:

english

File:

PDF, 81 KB

english, 2005

43

Preventing abnormalities in signal transduction of T cells in cancer: the promise of cytokine gene therapy

Karen Zier, Bernd Gansbacher, Silvia Salvadori

Journal:

Immunology Today

Year:

1996

File:

PDF, 417 KB

1996

44

Efficient and stable gene transfer of growth factors into chondrogenic cells and primary articular chondrocytes using a VSV.G pseudotyped retroviral vector

Stephan Vogt, Peter Ueblacker, Christopher Geis, Bettina Wagner, Gabriele Wexel, Thomas Tischer, Achim Krüger, Christian Plank, Martina Anton, Vladimir Martinek, Andreas B. Imhoff, Bernd Gansbacher

Journal:

Year:

2008

Language:

english

File:

PDF, 624 KB

english, 2008

45

Interleukin 2 gene transfer into tumor cells abrogates tumorigenicity and induces protective immunity

Journal:

Journal of Experimental Medicine

Year:

1990

Language:

english

File:

PDF, 758 KB

english, 1990

46

Angiogenese-Gentherapie mit AdVEGF 165 - Eine Art „Delay“ für Lappenplastiken?

Holzbach, T., Taskov, C., Neshkova, I., Holm, P. S., Konerding, M. A., Schams, D., Gänsbacher, B., Biemer, E., Giunta, R. E.

Journal:

Handchirurgie · Mikrochirurgie · Plastische Chirurgie

Year:

2005

File:

PDF, 359 KB

2005

47

IL2 gene transfer and its application in cancer

Journal:

Melanoma Research

Year:

1993

File:

PDF, 96 KB

1993

48

Gentherapie des Prostatakarzinoms

T. Brill, M. Barba, J. Breul, B. Gänsbacher

Journal:

Year:

2001

Language:

german

File:

PDF, 209 KB

german, 2001

49

Nerveninterponate zur Wiederherstellung der erektilen Funktion bei radikalen Beckenoperationen

F. May, S. Schoeler, M. Vroemen, K. Matiasek, M. Apprich, W. Erhardt, R. Hartung, B. Gansbacher, N. Weidner

Journal:

Year:

2005

Language:

german

File:

PDF, 623 KB

german, 2005

50

Non-invasive imaging of cardiac transgene expression with PET: comparison of the human sodium/iodide symporter gene andHSV1-tkas the reporter gene

Masao Miyagawa, Martina Anton, Bettina Wagner, Roland Haubner, Michael Souvatzoglou, Bernd Gansbacher, Markus Schwaiger, Frank M. Bengel

Journal:

European Journal of Nuclear Medicine and Molecular Imaging

Year:

2005

Language:

english

File:

PDF, 265 KB

english, 2005

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